Alzheimer’s, a Single Brain Scan Can Spot The Disease 98%
An abnormal protein accumulation in the brain causes Alzheimer’s disease. Two key proteins discovered in the human brain are amyloid and tau. When these proteins are destroyed by Alzheimer’s disease, however, they behave abnormally, resulting in plaque and tangles. There are tangles inside the plague.
Nerve cells are killed by these plagues because they damage them. The death of numerous cells causes the brain to shrink, which affects the hippocampus. But with the growth of new technologies scientists will soon develop a cure for Alzheimer’s disease and be soon able to conquer it. Recently research has shown that Alzheimer’s hope a single brain scan can spot the disease 98% of the time.
British scientists have developed a brain cell scan that can identify Alzheimer’s disease, which might be a milestone in early diagnosis. It’s predicated on an MRI scan and uses algorithms to examine structural features of the brain, including areas that haven’t previously been connected to Alzheimer’s disease.
It could detect alterations In parts of the brain that haven’t previously been connected to Alzheimer’s disease, such as the region of the brain that coordinates and regulates the physical activity and the part that controls vision and hearing.
The discovery will aid researchers in their understanding of what causes the condition and may potentially pave the path for the development of novel treatments. To diagnose the disease, doctors employ a variety of tests, including memory and cognitive exams, as well as brain scans. The scans are used to look for protein deposits in the brain as well as atrophy of the hippocampus, the memory-related part of the brain.
Organizing and processing them all can take several weeks. The novel method just takes one MRI scan, which can be performed on a standard 1.5 Tesla machine present in most hospitals. The researchers adopted an algorithm for diagnosing cancer tumours and applied it to the brain to create the scan. To examine each region, they divided the brain into 115 regions and assigned 660 distinct parameters, such as size, shape, and texture. The researchers then trained the programme to spot changes in these traits that might accurately indicate the presence of Alzheimer’s disease.
They subsequently tested their approach on over 400 individuals with Alzheimer’s disease in various stages, and even a healthy control group and those with various brain illnesses like frontotemporal dementia and Parkinson’s disease. They subsequently test that theory using data from over 80 individuals who were undergoing Alzheimer’s diagnostic testing at Imperial College Healthcare NHS Trust.
‘Presently, no other simple and publicly available approaches can predict Alzheimer’s disease with this amount of precision,’ said Professor Eric Aboagye, who directed the study. Numerous Alzheimer’s patients who visit memory clinics have several other neurological problems, but our method was able to tell who had Alzheimer’s and who didn’t. ‘Waiting for a diagnosis may be a nightmare for patients and their families. experimenter’s would be tremendously beneficial if we could shorten the time patients would have to wait, make diagnosis easier, and remove a few of the ambiguities,’ adds the researcher. ‘Our new technique could make it easier to find slightly earlier patients for clinical trials of new medications or lifestyle changes, which is currently challenging.’
‘While neuroradiologists already interpret MRI scans to aid in the diagnosis of Alzheimer’s disease, there seem to be likely to be features of the scans that are just not visible, even to specialists,’ said Dr Paresh Malhotra, a consultant neurologist at Imperial College Healthcare NHS Trust and a scientist in Imperial’s Department of Brain Sciences.
‘Using a computer to choose the texture and small structural characteristics of the brain that are affected by Alzheimer’s disease could increase the information we can collect from standard imaging techniques,’ adds the researcher.
Alzheimer’s disease is the most common form of dementia in the UK, affecting over half a million people.
Alzheimer’s disease strikes the majority of people around the age of 65, however, it can also strike people younger than that.
Memory loss and problems with thinking, problem-solving, and language are the most popular dementia symptoms.
Unfortunately, there is no treatment for Alzheimer’s disease, people aid from receiving a diagnosis as soon as possible.
It enables patients to seek assistance and support, as well as receive therapy to control their symptoms and make plans for the future.